Detalhe da pesquisa
1.
Structure of the Respiratory Syncytial Virus Polymerase Complex.
Cell
; 179(1): 193-204.e14, 2019 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31495574
2.
4'-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses.
PLoS Pathog
; 19(4): e1011342, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37068076
3.
Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses.
Proc Natl Acad Sci U S A
; 118(41)2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34561300
4.
Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice.
J Virol
; 96(6): e0218421, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35080423
5.
Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity.
PLoS Pathog
; 17(2): e1009371, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33621266
6.
A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo.
J Virol
; 95(22): e0112621, 2021 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34495697
7.
Development of an allosteric inhibitor class blocking RNA elongation by the respiratory syncytial virus polymerase complex.
J Biol Chem
; 293(43): 16761-16777, 2018 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30206124
8.
The Unstructured Paramyxovirus Nucleocapsid Protein Tail Domain Modulates Viral Pathogenesis through Regulation of Transcriptase Activity.
J Virol
; 92(8)2018 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29437959
9.
Fine mapping and characterization of the L-polymerase-binding domain of the respiratory syncytial virus phosphoprotein.
J Virol
; 89(8): 4421-33, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25653447
10.
Identification and characterization of the binding site of the respiratory syncytial virus phosphoprotein to RNA-free nucleoprotein.
J Virol
; 89(7): 3484-96, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25568210
11.
SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19.
bioRxiv
; 2022 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169793
12.
Orally efficacious lead of the AVG inhibitor series targeting a dynamic interface in the respiratory syncytial virus polymerase.
Sci Adv
; 8(25): eabo2236, 2022 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35749502
13.
SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model.
Nat Commun
; 13(1): 4416, 2022 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35906230
14.
4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication.
Science
; 375(6577): 161-167, 2022 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34855509
15.
Progress and pitfalls of a year of drug repurposing screens against COVID-19.
Curr Opin Virol
; 49: 183-193, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34218010
16.
SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy.
bioRxiv
; 2021 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972945
17.
4'-Fluorouridine is a broad-spectrum orally efficacious antiviral blocking respiratory syncytial virus and SARS-CoV-2 replication.
bioRxiv
; 2021 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031658
18.
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets.
Nat Commun
; 12(1): 6415, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34741049
19.
Viral evolution identifies a regulatory interface between paramyxovirus polymerase complex and nucleocapsid that controls replication dynamics.
Sci Adv
; 6(10): eaaz1590, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32181359
20.
High-Throughput Screening Assay to Identify Small Molecule Inhibitors of Marburg Virus VP40 Protein.
ACS Infect Dis
; 6(10): 2783-2799, 2020 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32870648